Electron microscopy technology of reticulocytes after sorting with magnetic beads

cell sorting technology plays an important role in detailed analysis of these cells as reticulocytes account for about 1% of all erythrocytes. Electron microscopy is the only means available for direct observation of the ultramicrostructure 2 of cells and tissues. However, specific pretreatment of samples is needed for some analyses (localisation 3 of cell protein, etc.) using an electron microscope. This bulletin presents the technology for cell sorting and subsequent observation of ultramicrostructure of cells.